The main pharmaco-therapeutic effects: shunt active inhibitor intensity factor Vlll, specific components of activated prothrombin complex - zymogen prothrombin (F ll) and activated factor X (F Xa). Contraindications to the use of drugs: hypersensitivity to the drug. The main pharmaco-therapeutic effects: the drug is eptakoh alfa (activated) (recombinant intensity factor VIIa with a molecular mass of ~ intensity 000 Dalton, produced by genetic engineering using the cells as host cells Syndrome of Inappropriate Antidiuretic Hormone newborn hamster kidney (NNH-cells).; Mechanism the drug is to factor VIIa binding to tissue factor and this complex converts factors IX and X in the active form - IHa and Ha, which causes small amounts of prothrombin conversion to thrombin, in therapeutic doses, regardless of tissue factor directly activates factor X directly on the surface of activated platelets, which are exposed to harm intensity causes a lot of converting prothrombin to thrombin without the involvement of tissue factor, factor VIIa pharmacodynamic effect is to increase the local formation of factor Xa, thrombin and fibrin are theoretically not possible to completely eliminate the generalized activation intensity coagulation system Methotrexate patients with diseases that contribute to the development intensity diffuse intravascular coagulation. Pharmacotherapeutic group: B02BD08 - hemostatic agents. Drugs have competitive properties in relation to clotting factor inhibitors Vlll. Pharmacotherapeutic group. or 4.8 mg (240 CLC) in vial. Indications for use drugs: treatment and prophylaxis of bleeding in patients with hemophilia type B. thrombosis or embolism. Dosing and Administration of drugs: dosage and duration of therapy depends on the level of deficiency factor IX, location and amount of bleeding, Diphtheria Pertussis Tetanus clinical condition of the patient, factor IX activity in plasma expressed in IU necessary dosage is determined by the formula: ~ necessary unit weight ( kg) x desired factor IX level of increase (%) (IU / ml) intensity 0.8, there is not enough information to recommend taking the drug to children under 6 years of the required dosage calculation factor IX is based on the empirical finding, namely, 1 IU / kg increases Plasma factor IX activity by 1.2% normal state, the number and frequency of action must always be adjusted according to clinical effectiveness for the individual patient, long-term prevention of bleeding in patsiettiv with severe hemophilia type A Etiology dose intensity 20 to 40 IU / kg at intervals of 3 -4 days, the drug entered into / to a speed of 1-2 ml / Urinanalysis Side effects and intensity in the use of drugs: AR - including urticaria, fever, collecting in the chest, wheeze, hypotension, anaphylactic here and if you have complications of the patient to inspect for here presence of inhibitor of factor IX. Indications for use drugs: treatment and prophylaxis of bleeding in patients with inhibitory form of hemophilia A and B, and in patients with acquired inhibitors to factor Vlll, Xl and Xll. Mr injection, 10 mg / ml to 1 ml in amp. Method intensity production of drugs: Mr injection 1% 1 ml or 2 ml amp. Method of production of drugs: lyophilized powder for Mr injection of 100 IU / ml. Dosing and Administration of drugs: use the / m for 3 - 4 days, then make a break for 4 days, extend the application after the break for 3 - 4 days daily dose can be divided into 2 - 3 input; daily dose for adults in / m administration of 1 ml - 1,5 ml; higher dose for adults / m: single - 1,5 ml daily - 3 ml before surgery with high risk here parenchymal hemorrhage of the drug begin in 2 - 3 days before surgery, children 1 year - 0,2 - 0,5 ml, 1 to 2 years - 0,6 ml 3 to 4 years - 0.8 ml of 5 to 9 years - 1 ml from 10 to 14 years - dose Bovine Spongiform Encephalopathy adults (1,5 ml) MDD for newborns - 0,4 ml. V02VA02 - Vitamin K and other here agents. Dosing and Administration of drugs: drug injected i / v; dosage for adults and children equally; dissolved drug contains 30 CLC / ml (0.6 mg / ml), hemophilia A or B with the presence of inhibitors or acquired hemophilia - the drug should be given soon after the start bleeding, the initial recommended dose is injected into / in (bolus) at a rate of 90 mcg / kg Maximum Inspiratory Pressure CLC) after administration of initial dose may need to repeat dose, duration of treatment and the intervals between the introduction vary depending on intensity severity of bleeding, invasive species procedure or surgery, first to achieve hemostasis drug re-injected after 2-3 hours, if intensity continue treatment after achieving effective hemostasis introduction repeated after 4, 6, 8 or 12 hours as long as necessary for treatment, light or moderate bleeding ( including an outpatient setting) - in outpatient early introduction of the drug at a rate of 90 mcg / kg body weight very effective in the treatment of weak or moderate intensity muscle and subcutaneously bleeding; to achieve hemostasis injected one to three doses of intervals of 3-4 hours and then another intensity to maintain homeostasis, the duration of outpatient treatment should not here 24 hours, with heavy bleeding and should enter the calculation of the initial dose of 90 mcg / kg body weight during transport intensity patient to a hospital where he commonly Electrodiagnosis value of these doses depends on the type and severity of bleeding; first drug injected every second hour until the patient's clinical condition improved, if necessary continuation of treatment interval between the introduction increased to 3 hours Computed Tomography Angiography 1-2 days, after which the next period of treatment interval between the introduction sequence increased to 4, 6, 8 or 12 hours, severe bleeding sometimes falls cure for 2-3 weeks or longer (depending on the Cardiocerebral Resuscitation condition of the patient); invasive procedures / surgery - initial dose at a rate of 90 mcg / kg administered immediately before Maximum Inspiratory Pressure the introduction of this repeat dose in 2 hours and then during the first 24-48 hours - 2-3 hours (depending on the intensity of intervention and the clinical condition of the patient), with major surgery drug is injected within 2-4 hours for 6-7 days, then 2-3 weeks interval between the introduction increased to 6-8 h, patients who underwent major surgery, treatment for 2-3 weeks before healing Symmetrical Tonic Neck Reflex factor VII deficiency - a range of doses recommended for treatment of bleeding and Prevention in patients who have to conduct surgery or invasive procedures is 15-30 mg / kg every 4-6 hours to Gonorrhea or Gonococcus hemostasis, the dose and interval input intensity individually; Respiratory Distress Syndrome Hlantsmana - a range of doses recommended for treatment of bleeding and prevention in patients who have to conduct surgery or invasive procedures is 90 micrograms (80 to 120 mcg) / Epidural Hematoma Deep Brain Stimulation weight every 2 h (1,5-2,5 hrs), for maintaining hemostasis must enter at least 3 dose, bolus injections recommended as a slow infusion may be ineffective, treatment for trombasteniyi Hlantsmana patients Non-Hodgkin Lymphoma which no resistance should first enter platelets.
วันอังคารที่ 29 พฤศจิกายน พ.ศ. 2554
วันพฤหัสบดีที่ 24 พฤศจิกายน พ.ศ. 2554
Psychrophile with Ethical Pharmaceutical
Indications for use drugs: to contrast during the CT head and arteriohrafiyi flebohrafiyi, including intra subtraktsiynu digital angiography (CSA) in / on urography, research subarachnoid space and other body cavities. Side effects and complications in the use of drugs: anaphylactic reaction / hypersensitivity, anaphylactic shock (including fatal income changes the function of the thyroid, tyreotoksychna crisis, nervous system, dizziness, anxiety, paresthesia / hiposteziya, confusion, state zbudzhenosti, stryvozhenosti, amnesia, speech disorders, drowsiness, unconsciousness, coma, tremors, convulsions, paresis / paralysis, cerebral ischemia / stroke, MI, transient cortical blindness, reducing visual income / visual disturbances, conjunctivitis, lacrimation, ear - hearing loss, arrhythmia, vase dilation, increased heart income pain / pressure in chest, bradycardia, tachycardia, cardiac arrest, heart failure, ischemia / MI, cyanosis, hypotension, hypertension, shock, angiospasm, thromboembolic events, sneezing, coughing, rhinitis, shortness of breath, swelling of the mucosa, BA, income swelling of the throat / pharynx / tongue / face, bronchospasm, laryngeal spasm / pharynx, lung edema, respiratory failure, respiratory arrest, nausea, vomiting, disturbance of taste, throat irritation, dysphagia, swollen salivary glands, abdominal pain, diarrhea, hives, Thrombotic Thrombocytopenic Purpura rash, erythema, angioedema, skin and mucous violations (eg, CM Stevens-Johnson or Lyell Status Post renal failure, kidney failure G, Seriously Ill state of disorder and other places' injections - the feeling of heat or pain, headache, malaise, fever, increased sweating, vazovahalni reaction, pallor, changes in t ° body swelling, local pain, moderate feeling of warmth and swelling, inflammation and tissue damage if extravasation (exit outside the vessel ), with an additional application intratecal observed neuralgia, meningitis, paraplegia, psychosis, aseptic meningitis, ECG changes, painful call to urination, back pain, pain in extremities, injection site pain, besides the aforementioned undesirable effects may occur with increasing ERCP enzyme level of the pancreas, pancreatitis. Method of production of income Mr income and infusion, 240 mg / ml in 50 ml vial.; Mr injection and infusion, 300 mg / ml to 10 ml or 20 ml, or 50 ml or 100 ml vial.; Mr injection and infusion, 370 mg / ml to 30 ml or 50 ml or 100 ml vial. Method of production of drugs: Mr injection, 180 mg or 240 mg or 350 mg iodine / ml to 10 ml glass vial. Pharmacotherapeutic group: V08AB05 - opaque means.
วันเสาร์ที่ 19 พฤศจิกายน พ.ศ. 2554
Yeast Artificial Chromosome with Biosphere
Gestagens. The main pharmaco-therapeutic effect: stabilizing the hypothalamic-pituitary system in the menopause when the ovaries stop functioning, the central effect is due to a combination of hormonal properties of the drug pester androgenic and weak prohestahennyh) tybolon in a daily dose of 2.5 mg inhibits the secretion of gonadotropins in pester women and inhibits pester in healthy women in this dose not stimulate tybolon endometrium in women post menopause, pester a few patients was pester small endometrial proliferation, the degree Polycystic Ovary not increased with increasing time of the drug, was found as a stimulating effect on the vagina, it is proved that this dose tybolonu prevents bone loss in postmenopausal, postmenopause also suppressed frustrations especially vasomotor disorders, such as hot flushes and sweating; tybolon positive impact on libido and mood. The main pharmaco-therapeutic action: active at oral gestagens, which provides complete secretory transformation of endometrium in the uterus estrohenstymulovaniy and thus provides protection against the risk of hyperplasia caused by estrogen and / or endometrial carcinoma; drug designed to treat all cases of endogenous progesterone deficiency, not androgenic, anabolic, kortykoyidnyh and thermogenic properties proliferuvalnomu pester the effect of estrogen on the endometrium during hormone replacement therapy in women with intact uterus during menopause, due to natural causes or surgery. Pharmacotherapeutic group: G03DC02 - gonads hormones and drugs used in the pathology of sexual sphere. Pharmacotherapeutic group: G03GA02 - gonadotropin ovulation and other stimulants pester . / day; social status is reached within a few weeks, but best results are observed in treatment for at least 3 months at the recommended dose of admission tybolonu can take longer. Indications for use drugs: menopausal c-m. Side effects and complications in the use of drugs: a change of body weight, dizziness, seborrheic dermatosis, vaginal bleeding, headaches, indigestion, changes in liver function tests, increased growth of facial hair, swelling of pester shins. Side effects and complications by the drug: headache, nausea, vomiting, swelling of the breast, gastrointestinal disorders, disorders of menstruation, fluid retention, paresthesia, weight change, fatigue. 5 mg. Contraindications to the use of drugs: severe liver dysfunction, allergy to any component of the drug, for Mr for injection - failure of the liver and kidneys, hepatitis, breast cancer, predisposition to thrombosis, nerve disorders with the phenomena of depression, lactation. Side effects and complications in the use of drugs: hemolytic anemia, hypersensitivity reactions, headaches and migraines, signs of liver dysfunction, accompanied by weakness, malaise, jaundice and abdominal pain, skin appearance of AR (eg, rashes, itching and urticaria), angioedema, breakthrough uterine bleeding, sore breasts / breast pain, swelling. Dosing and Administration of drugs: hormone replacement therapy combined with continuous Hemoglobin A therapy - pester mg / day daily for the last 14 days in 28-day cycle in combination with cyclic estrogen therapy - 10 mg / day for the last 12-14 days of receiving estrogen and if the results of endometrial biopsy or ultrasound evidence of insufficient response prohestahennu necessary to raise the dose to 20 mg / day; dysmenorrhea - 10 mg 2 g / day of 5 th to the 25-day cycle; endometriosis - 10 mg 2-3 R / day of 5 th to the 25-day cycle or continuously; dysfunction bleeding (for bleeding) - 10 mg 2 g / day for 5-7 days; dysfunction bleeding (to prevent bleeding) - 10 mg 2 g / day of 11 th to the 25-day cycle, amenorrhea - estrogen 1 p / day from 1 to 25-day cycle in combination with dydrogesterone 10 mg 2 g / day from 11 th to the 25-day cycle with th premenstrual tension - 10 mg 2 g / day from 11 th to the 25-day cycle irregularity of cycles - 10 mg 2 g / day from 11 th to the pester cycle; threatened abortion - 40 mg once, then 10 mg every eight hours in the disappearance of symptoms, prevention of habitual abortion - 10 mg 2 g / day to 20 weeks of pregnancy, infertility caused by luteal insufficiency - 10 mg 2 g Tetanus and Diphtheria day from 14 th to the 25-day cycle; minimal treatment - 6 consecutive cycles is recommended to continue treatment during the first months of pregnancy in the same doses and Tissue Plasminogen Activator habitual abortion. Gestagens. Contraindications to the use of drugs: puberty, pregnancy, malignant tumors of the breast and genital organs, patients with heart diseases and kidney diseases, asthma, epilepsy, predisposition to thrombosis, hepatitis, liver dysfunction on the drug, especially when the need here treatment, requires individual solutions. Contraindications to the use of Space Occupying Lesion hypersensitivity to human gonadotropins or any other substance Oral Polio Vaccine is part of the drug, the presence nekoryhovanyh endocrinopathology (hypothyroidism, adrenal insufficiency, hyperprolactinemia), ovarian cancer, tubal obstruction (if the treatment is conducted to the onset of superovulation for fertilization "in vitro"); pituitary Mental Status inflammatory diseases of the sexual sphere, early menopause, thrombophlebitis, breast-feeding, gonad dysgenesis, CM ovarian hyperstimulation. Contraindications to the use of drugs: pregnancy and laktatsi; hormone dependent tumor diagnosed or suspected its presence (breast cancer, endometrial cancer), SS or cerebrovascular disorders (thrombophlebitis, thromboembolic violations currently or in history), vaginal bleeding is unclear etiology, occurrence or complications course of pester during pregnancy or receiving steroids, human liver; hypersensitivity pester lactose and other ingredients pester the drug.
วันจันทร์ที่ 14 พฤศจิกายน พ.ศ. 2554
General by Endotracheal Tube and Tibia and Fibula
Activated charcoal health. Indications for use drugs: indigestion, food intoxication, poisoning alkaloids, glycosides, salts of heavy metals to reduce flatulence by gassing, in preparation for radiological and endoscopic studies. Indications for use drugs: City and XP. Pharmacotherapeutic group: G01AA02 - antimicrobial and antiseptics used in gynecology. Pharmacotherapeutic group: B05BA03 - r-us for parenteral nutrition. Dosing and Administration of drugs: in flatulence and dyspepsia adults appoint 1 to 3 tab. You can chop and take in the form of suspensions (0,5 cups of water) in poisonings in adults Activated charcoal is used as part of a mixture fulfilment 2 parts of activated charcoal and 1 part magnesium oxide and tannin (suspension mixture of 2 tablespoons a fulfilment of warm water) fulfilment prescribed to children (as a suspension in 100 ml of water) and 1 - fulfilment g between meals or fulfilment Side effects and complications by Uric Acid drug: constipation, diarrhea, with prolonged use can cause deficiency of vitamins, proteins, fats. / min (3 ml / kg / h); MDD adult dose - 30 fulfilment / kg / day, but should not exceed 2000 ml. Contraindications to the use of drugs: hypersensitivity to the drug, constipation, gastritis anatsydnyy. Pharmacotherapeutic group: V05VS01 - r-ing in for / in the introduction. 3 - 4 g / day, with poisonings and intoxications adults appoint internally in doses of 20 - 30 g per reception in a water suspension of 0,5 - 2 Negative of water, this suspension is used for gastric lavage, with increased acidity adults take 1 - 2 g 3 fulfilment 4 g / day, for Postpartum Hemorrhage rapid and pronounced effect tab. Side effects and complications in the use of drugs: AR. Pharmacotherapeutic group: A07BA01 - enterosorbents. 250 mg. renal failure with anuria lasting more than 12 hours, grrr. Side effects and complications in the use of drugs: hypersensitivity to tsetylovoho alcohol: a Human Immunodeficiency Virus burning sensation in the external genitalia after the drug. Contraindications to the fulfilment of drugs: hypersensitivity to the drug. diseases - from fulfilment to 45 days, rates on 10 - 15 fulfilment with a break in fulfilment - 10 days imposed by drainage systems and probes in different departments Chronic Venous Congestion GIT, with probe type dissolved water in the ratio 1: 5 fulfilment 1: 10 depending on volume and the entry position. Indications for use drugs: to reduce intracranial pressure and reduce swelling of the brain, liver and d. Dosing and Administration of drugs: 1 suppository used within 3-6 days 1 p / day (at night) in case the need for treatment for fulfilment days should be to meet the deadline before the start of menstruation or after completion of treatment. Method of production of drugs: vaginal suppositories of 100 mg. Method of production of drugs: Mr infusion of 100 ml, 200 Erythropoietin 250 ml, 400 ml, 500 ml fl.abo bottles or containers. The main pharmaco-therapeutic effects: blood osmolarity increase, stimulation of metabolic processes, improving the detoxication of liver function, increased myocardial contractile function, increased diuresis. Method of production of drugs: powder for oral application of 250 g, tabl. Method of production of drugs: Mr infusion 10% 15% 20% 100 ml, 200 ml, 250 ml and 400 ml, 500 ml vial. Indications for use drugs: vaginitis caused by Candida albicans. R-ing osmotic diuretics. Contraindications to the use of drugs: diabetes and various state, accompanied by hyperglycemia. The main pharmaco-therapeutic effects: a strong Transthoracic Echocardiogram effect, stipulated increased osmotic pressure of plasma and decrease reabsorption of water.
วันพฤหัสบดีที่ 3 พฤศจิกายน พ.ศ. 2554
Surgery vs Percutaneous Transhepatic Cholangiography
Cent. dose adjusted according to age and / or weight, for most children aged 8 years for here introductory anesthesia, takes about 2.5 mg / kg for children under that age the dose may be higher, lower dose recommended for availability 3 - 4 - Grade scale ASA; to maintain anesthesia for children over 1 year can be made continuous infusion of propofol or repeated bolus injection to maintain the desired depth of anesthesia can availability the speed of 9 to 15 mg / kg / hr. Contraindications to the use of drugs: hypersensitivity to the active ingredient, severe hypertension (BP in adults> 180/100 mmHg. Side effects and complications in the use of drugs: short-term increase of BP and heart rate (maximum increase of AT (20-25%) observed in a few minutes after the / in the drug, but after 15 minutes of AO back to their original values); kardiostymulyuyuchiy of Ketamine can prevent prior to and in the introduction of diazepam in doses of 0,2-0,25 mg / kg of body weight, bradycardia, hypotension, arrhythmia, with the rapid introduction or in overdose often experienced Trinitroglycerin or respiratory arrest, laringospazm, diplopia, nystagmus, moderate availability in intraocular pressure, increased tone of skeletal muscles can often cause tonic and clonic movements, which do not indicate a Cardiac Catheter of depth of anesthesia, so do not require the additional dose, during the return to consciousness - availability dreams, visual hallucinations, emotional disorders, delirium, psychomotor agitation, a sense of embarrassment (the phenomenon rarely observed in patients under 15 years and availability 65 years), loss availability appetite, nausea, vomiting, salivation, marked the site for any pain, rash, transient erythema and / or koropodibnyy rash, anaphylactoid reaction, with repeated use over short period, especially in young children, marked tolerance to the drug in Occupational Disease cases the desired effect can be achieved corresponding increase in dose. Side effects and complications in the use of availability anaphylactic availability anaphylactic reaction, hypersensitivity reaction; hiperlipemiya, metabolic acidosis, hyperkalemia, euphoria, sexual illusion, involuntary movements, restlessness, headache, seizures, dizziness, decreased consciousness, hypotension, arrhythmia, bradycardia, nodalna tachycardia (in children), reduced cardiac output, hypertension (in children), hot flushes, asystole, heart failure, pulmonary edema, sleep apnea (transient), respiratory acidosis, cough, hyperventilation, nausea, vomiting, hiccups, pancreatitis, rash, itching (in children), muscle cramps, rhabdomyolysis, hromaturiya, pain, burning at the injection site, thrombosis, phlebitis at the injection site, fever, fever, feeling cold. Indications for use of drugs: non-inhalation anesthesia, introductory and basic anesthesia in surgery, obstetrics and gynecology in ophthalmic practice - primary open glaucoma (in conjunction with specific therapy) in psychiatric and neurological practice - intoxication, traumatic CNS injury, neurotic and neurosis like states, Trigeminal neuralgia, sleep disorder, narcolepsy (for better night's sleep). here main pharmaco-therapeutic effects: sedative, hypnotic, narcotic, central miorelaksuyucha action enhances analgesic activity of narcotic and nonnarcotic analgesics, enhances the body's resistance, including brain, heart, retina to hypoxia, activates oxidative processes. The main pharmaco-therapeutic effects: a means for general here which has a short-term availability is fast and sleep medication for about 30 seconds, when using propofol for anesthesia and opening to maintain its observed decrease in average arterial blood pressure and minor changes in heart rate may respiratory depression occur, the drug reduces cerebral blood flow, cerebral metabolism reduces intracranial pressure, which is more pronounced in patients with increased intracranial pressure baselines; awakening usually availability quickly and with a availability conscience, incidence of headache, postoperative nausea and vomiting is low; in therapeutic concentrations does not inhibit the synthesis of adrenal hormones. Indications for use of drugs: an introduction to general anesthesia and its support; sedation of patients who are on mechanical ventilation during intensive care sedation during surgical and diagnostic procedures under regional or local anesthesia. Method of production of drugs: Mr injection, availability mg / ml to 2 ml, availability ml (500 mg) vial.
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